Sarcoma breast

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Breast sarcoma refers to a relatively heterogenous group of rare breast tumors which can include:. As a subgroup they comprises 0. They tend to present at a younger age than ductal or lobular carcinomas mean 45 years.

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Primitive sarcoma of the breast is a rare and challenging disease at high risk of recurrence and with poor prognosis. There are controversies in the diagnosis and management of such solid tumor due to its rarity and heterogeneity. This sarcoma is poorly responsive to both chemotherapy and radiotherapy, thus, surgery is the first and most important therapeutic approach.

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Delays in breast cancer diagnosis are associated with negative clinical effects. The main causes are protocol violations, clinical errors, radiological errors, pathological errors and patient fault. Although rare, breast lump that is clinically benign, but has undergone rapid growth should alert the clinician of the possibility of underlying sarcoma.

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Primary breast sarcoma PBS is a rare and heterogeneous group of malignancies with limited publications. We obtained data from the Surveillance, Epidemiology, and End Results Program and performed analysis to determine clinicopathological characteristics of PBS and estimate their associations with overall survival OS and cancer-specific survival CSS. Age, overlap or entire breast involvement, tumor histology, and tumor spread were associated with poor survival outcomes. In M0 patients, mastectomy was associated with worse survival outcomes compared with breast conservative surgery BCS adjusted hazard ratio [adjHR], 1.

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Unlike more common kinds of breast cancer which begin in the milk ducts, breast sarcomas begin in the connective tissue that supports the ducts and lobules of the breast. Breast sarcomas can be primary or secondary tumors. Just as with other forms of breast cancer, however, the reason for the development of a primary breast sarcoma is often unknown.

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Breast sarcomas are a very rare form of breast cancer. Less than one percent of all breast cancers that are diagnosed are sarcomas. Unlike most breast cancers which begin in the milk ducts, breast sarcomas begin in the connective tissue that supports the ducts and lobules of the breast.

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The rarity of this tumor limits most studies to small retrospective case reviews and case reports. Primary breast sarcomas are locally aggressive tumors as evidenced by the high rate of local recurrence when excisional surgery is performed. A contemporary multidisciplinary approach to therapy including surgery, radiation, and chemotherapy is advocated.

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New email address? Please contact us at CommentsPathOut gmail. Reisenbichler, M.

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Breast Cancer Research and Treatment. The clinical and pathological features of 33 previously untreated patients with primary breast sarcoma were retrospectively analysed to evaluate the prognostic significance of histologic variables on survival. The series comprised 17 cystosarcomas phyllodes and 16 stromal sarcomas excluding angiosarcomas.

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